Actos (pioglitazone) is a drug prescribed for the treatment of type 2 diabetes. Side effects include sore throat, low blood sugar, sinusitis, and headache. Drug interactions, dosage, and pregnancy and breastfeeding safety information are provided. Actos (pioglitazone) was once the bestselling Type-2 Diabetes medication in the world, but came under scrutiny after scientific studies revealed that people taking Actos have a much higher incidence of bladder cancer versus people taking other diabetes medications. As monotherapy or in combination with metformin or a sulfonylurea as an adjunct to diet and exercise to improve glycemic control. The NCI Dictionary of Cancer Terms features 8,360 terms related to cancer and medicine. We offer a widget that you can add to your website to let users look up cancer-related terms. Actionable Results. Cxbladder is a suite of non-invasive, simple to use bladder cancer detection tests that measure unique molecular signatures to help rule out, or diagnose bladder cancer. Bladder Cancer. Worldwide, bladder cancer is the ninth most common cancer, predicted to affect approximately 80,470 new patients in 2019 in the United States alone. Pioglitazone, sold under the brand name Actos among others, is a medication used to treat diabetes mellitus type 2. It may be used with metformin, a sulfonylurea, or insulin. Use is recommended together with exercise and diet. It is not recommended in diabetes mellitus type 1. It is taken by mouth. …cancer recurrence with pioglitazone should be considered. In preclinical studies, pioglitazone was associated with bladder tumors in male rats. Actos (pioglitazone hydrochloride) is a thiazolidinedione and increases the body's sensitivity to insulin. Actos is used for type 2 diabetes, not type 1 diabetes or diabetic ketoacidosis. Welcome to the Actos Legal Counsel website, dedicated to bringing justice to you and your family. Our mission is to provide the the latest up-to-date information on Actos lawsuits, settlements, and more.